Does Haloperidol Prophylaxis Reduce Ketamine-Induced Emergence Delirium in Children ? = هل الوقاية بالهالوبيريدول تحد من الهذيان الحادث بعد التخدير بالكيتامين في الأطفال ؟

Midazolam does not reduce emergence delirium after sevoflurane anesthesia in children.

BACKGROUND Behavioral disturbance in children following sevoflurane anesthesia is a relatively frequent event. The aim of this study was to evaluate whether a higher dose of preoperatively administered rectal midazolam compared with a lower would alleviate this phenomenon. Furthermore the impact of these two doses of midazolam on sedation at induction of anesthesia was compared. METHODS A tot...

Delirium risk screening and haloperidol prophylaxis program in hip fracture patients is a helpful tool in identifying high-risk patients, but does not reduce the incidence of delirium

BACKGROUND Delirium in patients with hip fractures lead to higher morbidity and mortality. Prevention in high-risk patients by prescribing low dose haloperidol is currently under investigation. METHODS This prospective cohort surveillance assessed hip fracture patients for risk of developing a delirium with the Risk Model for Delirium (RD) score. High-risk patients (score ≥ 5 points) were tre...

Does Dexmedetomidine Reduce Delirium by Improving Sleep?

Delirium is a common complication in intensive care unit (ICU) patients and its occurrence is associated with worse outcome (Inouye et al. 2014; Abelha et al. 2013). Sleep disturbances are considered one of the important risk factors of delirium development (Flink et al. 2012). Recent evidence shows that dexmedetomidine, either at sedative or non-sedative doses, can improve sleep quality and re...

Dexmedetomidine Prophylaxis for Patient with a History of Emergence Delirium

Haloperidol: A Novel Use in Ketamine Induced Postoperative Fulminant Psychosis

We report a case of severe/fulminant psychosis in an intellectually disabled healthy teenage female operated for the fracture shaft of the femur after post polio residual para-paresis under spinal anaesthesia. For intra-operative sedation, injection ketamine was used in subanaesthetic doses following midazolam premedication. Postoperatively she developed severe psychosis for which injection dia...